I think that it is easy to give up and become depressed and cynical.
it happens to me, even. there are only so many blatently racist comments that I can listen to before giving up and going home, but then, looking at the bigger picture, the falling IMRs across the globe, and I see that the war against endemic poverty is one that we are slowly winning.

Unicef, Fair Trade, Amnesty International. These are the big 3 that deserve our support, I think.

Also, any group doing the things that Unicef does as an NGO.