Trey Parker is a writer/cartoonist and one of the creators of South Park. His mockery of Mormonism and Scientology have landed him in hot water a few times. Chris Ofili and Andres Serrano are the artists behind Piss Christ and The Sacred Virgin Mary that kicked off all that "what is art?" nonsense in NYC 10 years back or so.

For giggles I really should have included Richard Dawkins and Neil DeGrasse Tyson on that list as well.

Point being that, if it's wrong to provoke Muslims, provoking Christians is equally wrong (or should be).